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Rapid urease test : ウィキペディア英語版 | Rapid urease test
Rapid urease test, also known as the CLO test (Campylobacter-like organism test), is a rapid diagnostic test for diagnosis of ''Helicobacter pylori''. The basis of the test is the ability of ''H. pylori'' to secrete the urease enzyme, which catalyzes the conversion of urea to ammonia and carbon dioxide. ==Process== The test is performed at the time of gastroscopy. A biopsy of mucosa is taken from the antrum of the stomach, and is placed into a medium containing urea and an indicator such as phenol red. The urease produced by ''H. pylori'' hydrolyzes urea to ammonia, which raises the pH of the medium, and changes the color of the specimen from yellow (NEGATIVE) to red (POSITIVE).
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